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Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease

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Introduction Coronaviruses are a large family of viruses in humans and animals, including Middle East Respiratory Syndrome (MERS-CoV), Severe Acute Respiratory Syndrome (SARS-CoV), and coronavirus disease 2019 (SARS-CoV-2 or COVID-19)