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Smoking is known for its negative impact on health, more often associated with lung cancer and heart disease

'Old Toad' cigarette-style sweets, France, 1995-1996 maker: Ferton-France SA 'sweet cigarette' style confectionary sticks with fictitious brand name of "Old Toad", one of five different packets, in packaging that accurately parodies that of real cigarettes, manufactured by Ferton-France S.A., France, 1995-1996

While several associations of cigarette smoking with cognitive function and brain structures have been established 30,31,32 , no consensus has been reached on the exact causal relationship between brain development and smoking in adolescence and its underlying neurobehavioural mechanisms remain elusive