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The costs to develop the VLN strain of tobacco, scale its production, conduct scientific studies on its effectiveness, obtain regulatory approvals, secure wide distribution networks, and create effective marketing have been and continue to be enormous

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However, tobacco and menthol were excluded, raising fears that even the FDA documented: Several comments argued that data suggest that even if youth currently prefer fruit and sweets to mint and menthol, this does not mean that youth do not still find mint and menthol to be appealing flavors. Menthol is responsible for the flavor of mint and has a cooling and mild anesthetic effect