what did they smoke before tobacco has Made the World it is Today Evolution of Smoking: from Cigarettes

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Nornicotine in the tobacco plant is predominantly formed by enzymatic demethylation of nicotine [28, 29], a process that appears biased toward the ( R )-nicotine enantiomer and leads to an observed wide variation in the ( R )/( S )-ratio of tobacco-derived nornicotine (475%) [30, 31] which would not match the ( R )/(S)-ratio of the nicotine from the same plant (0.11.2%) [32]

Cataracts Smoking doubles to triples the risk of cataracts, the leading cause of blindness worldwide, especially for heavy smokers

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