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Pipe tobacco smoke contains the same toxic and carcinogenic compounds as cigarette smoke, and exposure causes heart disease, stroke, lung cancer, and premature death in non-smokers

[2]This analysis identified over 1,500 unique chemical compounds (a smaller number than the 400,000 compounds reported by the Vaping Industry Trade Association)

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While there is some evidence generally showing small effects that using another nicotine product first can lead to cigarette smoking, prior use of another nicotine product does not appear to be a major driver of becoming a regular smoker