long term effects of tobacco on the body Memorial Regional Health: E-cigarettes a pathway to addiction — Teen use e-cigarettes is rising, along with risks for long-term health consequences Tobacco effects on the body

On the other hand, the difference is huge

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Khaldi T, Chekchaki N, Rouibah Z, Chouala K, Cheniti H, Boumendjel M, Taibi F, Messarah M, Boumendjel A (2022) Preventive effects of oral administration of Nigella sativa oil against smokeless tobacco induced toxicity and oxidative stress in the liver and kidney of allergic asthma induced rats

A cross-sectional analysis of a national population-based study found that exposure to secondhand smoke may be associated with increased odds of cognitive impairment, with those with higher cotinine concentrations being at a higher risk of cognitive impairment compared to those with lower cotinine concentrations