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Biotechnol Bioeng 103:706714

These include: A cough that doesnt go away or gets worse over time Chest pain or discomfort Fatigue Shortness of breath Wheezing Hoarseness Difficulty swallowing Loss of appetite Recurrent lung infections, including pneumonia Unexplained weight loss Swelling of the face and/or neck Other tests, like sputum cytology or endobronchial ultrasound, can be performed if imaging studies are negative or inconclusive

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