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Studies were deemed high quality on MMAT, CONSIDER, or MORI if they met 50% of the relevant criteria, consistent with previous reviews recently undertaken [17, 20]

Some cigarette components and their metabolites such as Benzo[a]pyrene, nicotine, and nicotine derived nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone were found to damage the local defence mechanism in the cervical epithelium 10

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