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Thus, adipose tissue, an important regulator of the cardiovascular system (118, 119), produces bioactive factors that regulate lipid levels and is involved in inflammation, oxidative stress, and insulin resistance (120)

Ethics declarations Competing interests FN has received consulting fees from most pharmaceutical companies in the field of hypertension and diabetes, as well as Haypp group and the Environment and Public Health Institute of Sweden related to his previous trial on the acute effects on nicotine in snus