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melaninogenica with oral cancer (Mager et al., 2005)

In a controlled Phase 3 trial of HUMIRA in subjects with polyarticular JIA who were 4 to 17 years, ALT elevations 3 x ULN occurred in 4.4% of HUMIRA-treated subjects and 1.5% of control-treated subjects (ALT more common than AST)

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Ewings motives were not altogether altruistic