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The third and fourth models allow me to look at the individual effects of the two variables RealPrice and RealExciseTax on Packs to determine if one has more influence than the other

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29,30,31 Between the period when many participants in the 1998 cohort were children (i.e., the 1940s) to when the 2018 cohort were children (i.e., the 1960s), knowledge of the harms of smoking and government responses increased dramatically, most notably indicated by the 1964 Surgeon Generals first report on the harms of smoking

Finally, proteins were detected by ECL reagents (BIO-RAD, USA), and densities of bands were quantified by Image J software