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[13] However, smoking prevalence and associated health issues continued to rise in the developed world in the first three decades following Richard Doll's discovery, with governments sometimes reluctant to curtail a habit seen as socially acceptable, as a result - and increasingly organised disinformation efforts by the tobacco industry and their proxies (covered in more detail below)

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Early intervention is needed to appropriately regulate these products, such that nicotine nave individuals do not initiate use and those currently using nicotine do not dual use with other tobacco products, according to the authors