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Although it has been found that long-term marijuana use may alter brain structure, it is not proven

Animal study Male C57BL/6 mice ranging from 8 to 12 weeks of age were purchased from the Jackson Laboratory (Bar Harbor, ME) and exposed to 4 non-filtered cigarettes (University of Kentucky research cigarettes, Lot number 1R5F), 5 days per week, for a total of 6 months

Effect of cigarette smoking on alveolar bone thickness and density in patients undergoing leveling and alignment of crowded lower anterior teeth: a controlled clinical trial