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relay tower HN-B1-12 North Kanawa: The location is displayed when observing from the top of the North Kanawa Observatory

Mechanism 2 Oxidative Stress Cigarette smoke contains over 4,000 chemical compounds, including potent free radicals reactive oxygen species (ROS) that damage cell structures

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In this communication, we first review the current knowledge about the mechanistic interaction between cigarette smoke and intestinal microbiota dysbiosis, which include the likely actions of nicotine, aldehydes, polycyclic aromatic hydrocarbons, heavy metals, volatile organic compounds and toxic gases, and then reveal the potential mechanisms of the lunggut cross talk and skin-gut cross talk in regulating the balance of intestinal microbiota and the interrelation of intestinal microbiota dysbiosis and systemic disorders