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Genotoxicity As a direct consequence of a reduction in carcinogenic toxicant emission, cMRTP aerosols should display significantly reduced mutagenicity and genotoxicity in standard cell-based assays, such as the Ames, in vitro micronucleus and the mouse lymphoma assays [32, 50]

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Second, we reviewed documents from 2000 to 2005 housed in the Legacy Tobacco Documents Library (Legacy Library) at the University of California, San Francisco.28 The Legacy Library contains 7 million documents related to different practices associated with tobacco products

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