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- Annular keratinopathic ichthyosis: a special subtype in which patients are born with an appearance similar to that of other keratinopathic ichthyoses, but subsequently progress to a less severe clinical form in which, in addition to diffuse hyperkeratosis at the level of the large folds, transient annular lesions with superficial desquamation are observed38 (Fig

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Titanic has left a lasting impression on cinema, thanks in large part to becoming the world's highest-grossing film at the time of release and turning leads Leonardo DiCaprio and Kate Winslet into bona fide movie stars