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32 Nicotine also affects the vasculature by inducing vasoconstriction, resulting in elevated blood pressure and impaired wound healing in the microvasculature, which is mediated primarily through activation of the homomeric 7 nicotinic acetylcholine receptor expressed on endothelial cells and 1 receptors on vascular smooth muscle cells

Amid so much uncertainty and harm coming from the mushrooming market for novel, unregulated products, some researchers raise the concern that banning legal vapes would make the problem worse, not better

Some companies also offer support programs for employees who want to quit smoking

Over time, the vessels no longer hold up to the pressure and rupture