does tirzepatide cause kidney damage Interplay of Chronic Disease and the Effects of in Patients With Heart Failure, Preserved Ejection Fraction, and Obesity: The SUMMIT Trial Is Tirzepatide a Stimulant? Mechanism

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In the Study of Tirzepatide in Participants with Heart Failure with Preserved Ejection Fraction with Obesity (SUMMIT) trial, tirzepatide significantly reduced the risk of death from cardiovascular causes or worsening heart failure events in patients with heart failure with preserved ejection fraction (ejection fraction 50% and above) and obesity (BMI 30 kg/m 2 ), compared with placebo (HR 0.62

doi: 10.1111/cen.14081 25 LugerA

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