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Other warning signs include persistent dizziness, fainting, or severe muscle weakness, which could indicate a blood pressure drop or an electrolyte imbalance

The treatment significantly improved stool frequency and overall quality of life, compared with a placebo treatment ( Although senna is generally considered safe, it can lead to adverse effects when used for long periods at high dosages

Wrinkle reduction Yes Regeneration and healing Yes Antioxidant effects Yes Improved skin elasticity Yes Safety of use Yes Scientific data and sources Research summary Level of evidence Preliminary Number of included studies: 20 8 studies 5 studies 4 studies 1 study 1 study 1 study Final comment: Although systematic literature analyses and results from in vitro and animal model studies indicate the effectiveness of GHK-Cu in skin regeneration and wrinkle reduction, there are no direct randomized controlled trials in humans

Dean, R