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However, for an individual whose primary struggle is an overactive gut, this side effect may potentially translate into a therapeutic benefit

Hryciw DH, Patten RK, Rodgers RJ, Proietto J, Hutchinson DS, McAinch AJ (2024) GPR119 agonists for type 2 diabetes: past failures and future hopes for preclinical and early phase candidates

Shortly after its success with diabetes treatment, Gotthardt and other scientists realized in the mid-2000s that insulinomas, typically a clump of many beta cells, also contain a high amount of GLP1Rs, making exendin-4 an attractive candidate to help localize these pesky tumors

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