semaglutide doesn't work for me Why Stopped Working: 5 Real Reasons & Fixes What Skipping a GLP-1 Dose

Over time, stress-driven cortisol spikes and lack of restorative sleep can push your body into a state where fat loss becomes extremely difficult, even with medication

Metabolic adaptation : The body naturally adapts to weight loss by reducing metabolic rate, a phenomenon sometimes called "adaptive thermogenesis." This biological response is expected and can slow or plateau weight loss even when medication and lifestyle factors remain consistent

Adopt a more balanced diet that focuses on fruits, vegetables, lean proteins, and whole grains

14-15 It is important to note that obesity is a chronic disease, and discontinuing semaglutide can lead to weight regain due to a decrease in lean mass and basal metabolic rate (BMR)