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In neurodegenerative conditions, the brain is unable to use glucose effectively due to both glial and neuronal changes in glucose transportation, in addition to changes in cellular respiration enzymatic activities, and insulin signaling [17]
Instead, therapeutic modulation of GSH must be tailored to disease context, reflecting the fundamental GSH paradox: whereas cancer therapy often seeks to deplete elevated GSH to induce oxidative stress and cell death, neurodegenerative and inflammatory diseases may require restoration of GSH homeostasis
Morning Sickness Nausea and vomiting are estimated to affect 70-85% of pregnant women during weeks 6-12 of pregnancy, but extreme morning sickness, only affects about 1% of all pregnancies Zofran is not approved for use during pregnancy
In addition to providing recommendations for achieving glycaemic control, current type 2 diabetes guidelines emphasise the importance of weight loss through lifestyle changes, surgical interventions or medications [6, 7]
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