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[99] In 2023, the FDA updated Ozempic labeling to warn of ileus following approximately 20 cases, including two deaths

for Wegovy, follow current SmPC guidance on reassessment) [6] Tolerability and side effects Blood pressure and metabolic parameters Psychological wellbeing and eating behaviours Important safety considerations include: GLP-1 medications are not recommended during pregnancy or breastfeeding

FDA approved the first GLP-1 RA in 2005, and there are now several in this class

Practical Research Considerations A few practical points come up repeatedly in the research literature and community discussion: Weekly cadence