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In our future work, we will examine the comparative effectiveness of alternative treatment options for obesity in patients who discontinue semaglutide or tirzepatide, to help patients and their clinicians make informed decisions. Cleveland Clinic is a nonprofit multispecialty academic medical center that integrates clinical and hospital care with research and education

Those with established cardiovascular disease might prefer semaglutide given its proven cardiovascular outcome data

After reviewing my case, we decided to transition to a physician-supervised tirzepatide treatment program with individualized dose escalation, scheduled follow-up appointments, and ongoing clinical monitoring

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