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Because of how angiogenic it is, theres some very serious theoretical risk, especially for people with cancer, Dr McGuire says

Unlike IGF-1 LR3 which has systemic effects and a long half-life IGF-1 DES is designed for site-specific application

[DOI] [PubMed] [Google Scholar] Jain SK, McVie R, Smith T

Since the valinomycin synthetase Vlm shows the same genetic architecture as Ces, it is tempting to speculate that the novel mechanism of non-ribosomal peptide assembly proposed in this study is not a specificity of the cereulide synthetase but a more common logic for biosynthesis of ester bond containing NRPS products, thereby contributing to biodiversity of natural depsipeptide products