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Combination therapy also produced favorable changes in multiple cardiometabolic risk factors and patient-reported quality of life while maintaining an acceptable safety profile consistent with previous experience for both medications

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As we continue to navigate the intricate balance between diet, pharmacotherapy, and cardiovascular risk, it is essential that future research prioritizes the development of integrative approaches that not only address the immediate challenges of obesity but also mitigate long-term cardiometabolic risks, ensuring that treatment strategies are both effective and sustainable