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About the SELECT trial SELECT was a randomised, double-blind, parallel-group, placebo-controlled trial designed to evaluate the efficacy of Wegovy (semaglutide 2.4 mg) versus placebo as an adjunct to standard of care for the prevention of MACE in people with overweight or obesity and established CVD with no prior history of diabetes

In STZ-diabetic mice, sALT and sLDH were significantly increased and the only sLDH was significantly inhibited by the treatment with sitagliptin

Fatigue is a common experience in the early weeks on a GLP-1 medication, often tied to reduced calorie intake and the body still adjusting