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doi: 10.1073/pnas.1922392117

The brain is also a major site of Mn deposition, with regional concentrations ranging from 0.16 to 0.46 mg/kg, the highest levels found in the globus pallidus and putamen, regions primarily responsible for motor control (Krebs et al., 2014)

Densities of both gels representing the oxidized proteins in control animals or MDMA-exposed rats were adjusted for comparable exposure levels of an internal control protein in 2 different gels

Upon receptor binding, it initiates Gq-coupled intracellular signaling, thus activating phospholipase C, generating inositol trisphosphate, and mobilizing intracellular calcium