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Counseling should emphasize shared decisionmaking and evidencebased care

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These data, in combination with findings from the Irwin test, in which AEF0117 (0 mg kg 1 , 2 mg kg 1 , 9 mg kg 1 and 36 mg kg 1 ) had no effect on spontaneous behavior in the home cage (Supplementary Tables 38), show that AEF0117 has no identifiable effects on behavior per se in rodents

Until around a decade ago, the standard of care for T2D involved the use of glucose-lowering drugs (GLDs) such as metformin, sulfonylureas, thiazolidinediones, meglitinides and -glucosidase inhibitors [8]