what is a melanotic macule macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Labial melanotic macule (brown spot

Olsen RHJ, DiBerto JF, English JG et al (2020) TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome

For example, elevated ATP levels promote lipid synthesis through the upregulation of enzymes like fatty acid synthase and acetyl-CoA carboxylase (ACC) and transcription factors such as sterol regulatory element-binding protein and liver X receptor (LXR)

Patients in Sandy Springs and Atlanta who suffered severe gastrointestinal injuries, stomach paralysis, or vision loss may have claims not only against drug manufacturers but also against prescribing physicians who failed to follow safe prescribing practices or warn patients about significant risks