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Celebrated for their weight loss and health benefits, these medications also raise concerns about access, cost, safety and ethics

Palsamy P, Sivakumar S, Subramanian S (2010) Resveratrol attenuates hyperglycemia-mediated oxidative stress, proinflammatory cytokines and protects hepatocytes ultrastructure in streptozotocin-nicotinamide-induced experimental diabetic rats

Rhythm Pharmaceuticals setmelanotide, gated by a REMS and genetic testing, signals how regulators may handle next-generation therapies with complex safety profiles