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[7] There are not enough studies on whether pills are effective in improving or eliminating symptoms

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Beyond the intervention to be evaluated, those designing such studies must consider whether the study should be focused on one or more long COVID phenotype or enroll more broadly, what phase after SARS-CoV-2 infection is the target for intervention (acute, early post-acute, post-acute), the optimal design and if relevant, randomization scheme, and the optimal outcomes, which in most cases are likely to involve a combination of patient-reported outcomes and biological measurements