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Acknowledgments This research was performed using equipment from the Core Centrum Genomic Technologies, Proteomics and Cell Biology in ARRIAM

Medicine & Engineering & Informatics Fusion and Transformation Key Laboratory of Luzhou City (XGY202407)

In UC, significant alterations in gut microbiota, known as microbial dysbiosis, are observed, characterized by reduced diversity in the phyla Firmicutes and Bacteroidetes, alongside an increase in Enterobacteriaceae