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Several peptides being studied have mechanisms that directly address this core problem: they promote new blood vessel formation (angiogenesis), reduce the inflammatory cascade that accelerates disc breakdown, and stimulate the cellular repair processes needed to rebuild damaged disc structures

There are also growing questions about the long-term effects of GLP-1s

The aim of this study was to assess the impact of MBS on CVD outcomes in patients with severe obesity and T2D compared to non-surgical patients with T2D treated with GLP-1 RA

The results indicated lipid-lowering potential with combined therapy of alogliptin [54]