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134 These observations underscore the complex and context-dependent effects of ERAD in adipose tissue, linking local proteostasis to systemic lipid homeostasis

L-Glutathione L-Glutathione is a naturally occurring tripeptide composed of the amino acids cysteine, glutamic acid, and glycine

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The unique, upstream approach taken by Mardinoglu and team to increase endogenous glutathione synthesis and reduce fatty liver (while supporting methylation balance) based on their work using personalized genome-scale metabolic models, is worth us considering in clinical practice