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In this review, we specifically focus on the MTHFR polymorphism and related methylation and folate effects on psychiatric diseases as well as the possibility of relationship between clinical phenotypes of MTHFR-related diseases and effectiveness of clinical treatment in psychiatric patients 11

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This raises a clinically relevant question: in the context of polypharmacy, might a history of -lactam allergy predispose patients to quinolone-induced DILI and/or SJS/TEN (e.g., from moxifloxacin)