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VRK2 overexpression elevated the interaction of SLC7A11 and Sec24C WT, but not Sec24C MUT (Fig
Subsequently, embryos of each group were cultured in vitro for a further 7 days with the culture medium changed every other day
Abbreviations AST: Aspartate transaminase ALT: Alanine transaminase UA: Uric acid TP: Total protein AL: Albumin AY: Amylase FR: Ferritin C: Cortisol -HB: Beta-hydroxybutyric acid Ht: Hematocrit CVD: Cardiovascular disease GRF: Glomerular filtration rate BW: Body weight BH: Body height BF: Body fat FFM: Fat free mass TBW: Total body water BMI: Body mass index BSA: Body surface area References Ezpeleta, M
The Connectivity Map approach compares the gene-expression signature a compound induces in cultured cells against a reference database of signatures, inferring which pathological patterns the compound might counteract
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