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In mammals, Indoleacetic-3-acid (IAA) is an important indole-derivative catabolized from dietary tryptophan by the intestinal microbiota, but intestinal dysbiosis can influence IAA production (13)

Provide stable energy levels due to slow carbohydrates

Tryptophan metabolites, such as 5-hydroxytryptamine and 3- hydroxyanthranilic acid, act as potential radical-trapping antioxidants and can protect cells from ferroptosis by eliminating lipid peroxidation [49]

Mir Ali, MD, board certified general surgeon, bariatric surgeon, and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA, who was not involved in the study, noted the following to Medical News Today: This study showed a reduction of MASH with semaglutide use