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Se han establecido dos fases para la suplementacin: una fase de carga de 20 g de CM por da o 0.3 g de CM/kg de peso corporal/ por da dividida en 4 tomas de 5 g cada una, seguida de una fase de mantenimiento 3-5 g de CM al da

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Acute kidney injury Experimental studies Ischemic acute kidney injury (AKI) in rodents and humans results in preferential damage of the distal segment of the proximal tubule (S 3 -segment) and the thick ascending limb of the loop of Henle, indicated by loss of brush borders, cell necrosis and apoptosis, since this part of the nephron heavily depends on medullary blood flow in order to preserve oxygen supply [179]