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It is injected under the skin of a patients stomach area, thigh or upper arm, and is to be used together with a reduced-calorie diet and increased physical activity

At 24 mg, the majority of participants achieved clinically meaningful weight loss thresholds, and by week 48, 95.7% of individuals treated with CT-388 lost a minimum of 5% of body weight, while 87% achieved reductions of at least 10%

It is worth noting that in addition to histamine intolerance, mast cell activation disorder (MCAD) is another condition that can lead to an excess release of histamine and other mediators from mast cells

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