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In the United States, there is a boxed warning of the possible risk, and those with personal or family histories of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 are therefore advised to avoid liraglutide, dulaglutide, exenatide extended release, and semaglutide

Maintaining motivation during the second half requires different strategies than the first half

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For example, a study published in the *New England Journal of Medicine* reported that individuals using the highest dose of Mounjaro lost an average of 22.5% of their body weight, a remarkable outcome compared to many other weight loss therapies on the market