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Comment: Commenters raised concerns about the potential burden, duplicative and resource-intensive efforts, and confusion for participants involved in the overlap between the ASM, the Transforming Episode Accountability Model (TEAM), and the Wasteful and Inappropriate Service Reduction (WISeR) models, highlighting that the overlap may create challenges for model implementation, evaluation, and attribution of quality and cost reduction outcomes for clinicians required to participate in all the three models

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Its unique mechanism of promoting angiogenesis while simultaneously reducing inflammation has made it a subject of intense research interest for tissue repair and regeneration applications