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Pfizers first marketed gene therapy, Beqvez was approved by Health Canada in January, and was featured in BioSpace s 5 Cell and Gene Therapy Decisions to Watch in 2024

They are optimal for their insulinotropic effect exclusively when glucose levels are elevated, thereby providing the capacity to decrease plasma glucose while mitigating the risk of hypoglycemia

Anthracycline-induced toxicity in this trial did not appear to be worsened by combination with VPA, and other toxicities are manageable providing some reassurance that any synergy in terms of efficacy will not be replicated in unwanted side effects

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