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One randomized, double-blind, placebo-controlled trial found no evidence that a daily antioxidant supplement containing 12 mg of -carotene, 500 mg of vitamin C, and 400 mg of vitamin E, when taken for up to 12 months, improved mental performance in elderly people (163)

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10,11 Curcumin Preclinical and in vitro data suggest that curcumin can inhibit DPP-4 activity and enhance glycemic control in diabetic animal models, potentially prolonging the active life of GLP-1, although this has not been confirmed in human mechanistic studies

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