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NHPN-1010 enhanced gap-prepulse inhibition of acoustic startle responsesindicative of diminished tinnitus-like deficitscoupled with a concomitant upregulation of GABAergic inhibition in the dorsal cochlear nucleus, relative to vehicle alone (saline)

These mostly hydrophilic modifications have yielded cyclodextrin derivates highly suitable for parenteral administration [Cyclodextrins used as excipients, 2017, EMA/CHMP/333892/2013, Committee for Human Medicinal Products (CHMP)]

Because semaglutide is dosed once weekly and a single vial can span weeks, BAC water is the documented standard published stability data show up to 28 days refrigerated