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Clinicians should conduct a thorough medical history and relevant physical examination for patients with pigmented lesions to identify possible adrenal, gastrointestinal, or genetic disorders that are commonly associated with these types of lesions

Previous data indicate assessing the activity of antioxidant enzymes in heterotopic tissues with different degrees of their regression, and this is important both for understanding the mechanisms of development and regression of endometrioid foci as well as for assessing the possibility of predicting disease course by the activity level of these enzymes

[31] Along with Ectodysplasin A, it has been shown to be involved in the differentiation of anatomical placodes, precursors of scales, feathers and hair follicles in vertebrates