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In comparison to earlier conjugations on human ferritin, where ~ 68 RBDs were bound per nanoparticle despite ~ 50 partially accessible cysteines, the engineered PfFt variants introduced 1219 accessible cysteines and enabled binding of up to 11 RBDs per nanoparticle

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This is helps to find out the compatibility between the donor and the recipient so that neither of them gets any harm in the process

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