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Initially Fab 3F52 was characterized in radioligand competition binding experiments using GLP-1R from various species in order to confirm the species specificity of mAb 3F52 shown previously by immunohistochemistry 25

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Finally, delivery of the classical chemotherapy drug paclitaxel (PTX) encapsulated in liposomes (ITP2-Lip/PTX) by intravenous administration significantly extended the survival of mice bearing GL261 orthotopic gliomas (Supplementary Fig

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