weight loss difference between semaglutide and tirzepatide vs for Treatment Tirzepatide vs. Semaglutide for Weight

However, it is unknown whether participants who were on the 3 mg dose at study end had previously been on a higher dose or had stayed on 3 mg throughout the study, and due to the length of the study, participants may not have needed to escalate from the lowest dose of oral semaglutide

Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on December 21st, 2025

Ozempic takes longer to build up in your system, with noticeable weight loss typically appearing after 8 to 12 weeks

Millions of Americans are struggling with their weight every day and find it hard to lose their excess weight through a healthy diet and regular exercise alone