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Body weight in the semaglutide group decreased by an estimated 6.8 kg more than placebo, confirming the expected weight loss effect, but the bone changes occurred in parallel rather than being fully explained by mechanical unloading from weight loss alone

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In individuals with CKD and/or chronic heart failure receiving RAAS blockers, predictors of recurrent hyperkalemia within 6 months of the first episode include initial hyperkalemia with a potassium (K) level of 5.6 mmol/L, an eGFR of 30%, follow-up testing should be performed

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